Alterations in the expression of or mutations in mouse tektins are correlated with defective sperm motility, a cause of male infertility.
At the protein level, TEKT5 was present in sperm and was enriched in the accessory structures of flagella.
Immunofluorescence confirmed that TEKT5 was localized throughout the sperm tail in flagellar accessory structures.
The expression pattern suggests that TEKT5 plays an important role in flagella formation during spermiogenesis as well as being implicated in sperm motility.
Structural component of ciliary and flagellar microtubules.
Forms filamentous polymers in the walls of ciliary and flagellar microtubules (By similarity).
Applications:Suitable for use in ELISA, Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:1000-1:2000Western Blot: 1:200-1:1000Immunohistochemistry: 1:25-1:100Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.05% sodium azide, 40% glycerol.
Specificity：Recognizes human TEKT5.
Isotype：IgG
Calc Applications Abbrev：E IHC WB
Calc Crossreactivity：Hu
Immunogen：Fusion protein corresponding to human TEKT5.
