84-4203-35　MEK-5 (Dual specificity mitogen-activated protein kinase kinase 5, MAP2K5) 100ul　323083

特徴

• The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family.
• This kinase specifically interacts with and activates MAPK7/ERK5.
• This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs).
• The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation.
• Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described.
• Applications:Suitable for use in ELISA and Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:2000-1:5000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.