The protein encoded by this gene is a mediator of mitochondrial fusion.
This protein and mitofusin 2 are homologs of the Drosophila protein fuzzy onion (Fzo).
They are mitochondrial membrane proteins that interact with each other to facilitate mitochondrial targeting.
Essential transmembrane GTPase, which mediates mitochondrial fusion.
Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission.
MFN1 acts independently of the cytoskeleton.
Overexpression induces the formation of mitochondrial networks
Applications:Suitable for use in ELISA and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:2000-1:5000Immunohistochemistry: 1:25-1:100Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.4, 0.05% sodium azide, 40% glycerol.
Specificity:Species Crossreactivity: mouse and rat