The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein.
This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins.
This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system.
It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis.
This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance.
This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease.
Alternative splicing results in multiple transcript variants encoding distinct isoforms
Applications:Suitable for use in ELISA and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:2000-1:5000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.05% sodium azide, 40% glycerol.
Specificity：Recognizes human BAIAP2. Species Crossreactivity: mouse and rat
