Angiopoietins are proteins with important roles in vascular development and angiogenesis.
All Angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor.
The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation.
It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability.
The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart.
Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Applications:Suitable for use in ELISA and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:2000-1:5000Immunohistochemistry: 1:25-1:100Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.05% sodium azide, 40% glycerol.
Specificity：Species Crossreactivity: mouse and rat
