84-4186-41　IL1R2 (Interleukin-1 Receptor Type 2, IL-1R-2, IL-1RT-2, IL-1RT2, CD121 Antigen-like Family Member B, CDw121b, IL-1 type II Receptor, Interleukin-1 Receptor beta, IL-1R-beta, Interleukin-1 Receptor Type II, CD121b, Interleukin-1 Receptor Type 2, Membrane Form) 50ul　320283

特徴

• The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family.
• This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands.
• Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine.
• This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12.
• Alternative splicing results in multiple transcript variants and protein isoforms.
• Alternative splicing produces both membrane-bound and soluble proteins.
• A soluble protein is also produced by proteolytic cleavage.
• Applications:Suitable for use in ELISA, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:1000-1:5000Immunohistochemistry: 1:25-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.