NF-kappa-B is a ubiquitous transcription factor involved in several biological processes.
It is held in the cytoplasm in an inactive state by specific inhibitors.
Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes.
NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB.
The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA.
Four transcript variants encoding different isoforms have been found for this gene.
Applications:Suitable for use in ELISA, Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:2000-1:5000Western Blot: 1:200-1:1000Immunohistochemistry: 1:25-1:100Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.4, 0.05% sodium azide, 40% glycerol.