The protein encoded by this gene is involved in the TGF-beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells.
The encoded protein is activated by BMP type 1 receptor kinase.
Three transcript variants encoding the same protein have been found for this gene.
Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase.
SMAD5 is a receptor-regulated SMAD (R-SMAD).
May form trimers with the co-SMAD SMAD4.
Interacts with PEBP2-alpha subunit and SMURF1.
Interacts with SUV39H1 and SUV39H2.
Interacts (via MH2 domain) with LEMD3.
Interacts with WWP1.
Applications:Suitable for use in ELISA, Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:1000-1:2000Western Blot: 1:200-1:1000Immunohistochemistry: 1:25-1:100Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.05% sodium azide, 40% glycerol.
Specificity：Species Crossreactivity: mouse and rat
