84-4183-22　ADD1 (ADDA, Alpha-adducin, Erythrocyte adducin subunit alpha) 50ul　304883

特徴

• Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma).
• Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure.
• Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region.
• Alpha- and gamma-adducins are ubiquitously expressed.
• In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues.
• Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C.
• Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described.
• Applications:Suitable for use in ELISA, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:500-1:5000Immunohistochemistry: 1:50-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.