THNSL2 (threonine synthase-like 2), also known as TSH2, is a 484aa protein belonging to the threonine synthase family.
Utilizing pyridoxal phosphate as a cofactor, THNSL2 may function as a catabolic phospholyase on gamma and beta phosphorylated substrates.
THNSL2 may also degrade O-phospho-threonine to alpha-ketobutyrate, ammonia and phosphate.
Existing as four alternatively spliced isoforms, THNSL2 is encoded by a gene mapping to human chromosome 2p11.2.
As the second largest human chromosome, chromosome 2 makes up approximately 8% of the human genome and contains 237 million bases encoding over 1400 genes.
A number of genetic diseases are linked to genes on chromosome 2.
Harlequin icthyosis, a rare skin deformity, is associated with mutations in the ABCA12 gene.
The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8 gene defects.
An extremely rare recessive genetic disorder, Alström syndrome, is related to mutations in the ALMS1 gene.
Applications:Suitable for use in ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：150ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.3, 0.09% sodium azide, 50% glycerol.
Specificity：Recognizes human THNSL2. Species Crossreactivity: mouse and rat
