84-4145-97　RTN3 (Reticulon-3, HAP, Homolog of ASY Protein, Neuroendocrine-specific Protein-like 2, Neuroendocrine-specific Protein-like II, NSP-like Protein 2, NSP-like Protein II, NSPLII) 150ul　332431

特徴

• Reticulon-3, also known as RTN3 or NSPL2, is a protein that in humans is encoded by the RTN3 gene.
• It is mapped to 11q13, which is between markers D11S4535 and D11S4627.
• This gene belongs to the reticulon family of highly conserved genes that are preferentially expressed in neuroendocrine tissues.
• This family of proteins interact with, and modulate the activity of beta-amyloid converting enzyme 1 (BACE1), and the production of amyloid-beta.
• RTN3 colocalized with BACE1 in neurons of human brain gray matter, and overexpression of RTN3 in vitro inhibited BACE1 activity and decreased amyloid precursor protein processing.
• Applications:Suitable for use in ELISA, Western Blot and Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.