The protein encoded by this gene localizes to centromeres, where it is essential for recruitment of CENP-A through the mediator Holliday junction recognition protein.
Expression of this gene is upregulated in several cancers, making it a putative therapeutic target.
Two transcript variants encoding different isoforms have been found for this gene.
OIP5 (Opa Interacting Protein 5) is a Protein Coding gene.
Among its related pathways are Chromosome Maintenance and Cell Cycle, Mitotic.
Applications:Suitable for use in ELISA, Western Blot.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.3, 0.09% sodium azide, 50% glycerol.
Specificity:Recognizes human OIP5.
Isotype:IgG
Calc Applications Abbrev:E WB
Calc Crossreactivity:Hu
Immunogen:Human OIP5 Species sequence homology: mouse