Glypican-5 is also known as GPC5 and is a 572aa protein.
Glypican-5 is primarily expressed in adult brain tissue (where it is localized to neurons), but is also detected in fetal brain, lung and liver.
Glypican-5 is a member of the glypican-related integral membrane proteoglycan family (GRIPS), which is characterized as having a core protein that is able to use glycosyl phosphatidylinositol to attach to the cytoplasmic membrane.
Upregulation of glypican-5 has been found in active multiple sclerosis plaques, suggesting that glypican-5 may be involved in pathogenesis of multiple sclerosis.
Upregulation of glypican-5 has also been recognized as having a strong correlation with lymphomas, as well as other tumors.
Applications:Suitable for use in ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.3, 0.09% sodium azide, 50% glycerol.
Specificity:Recognizes human GPC5. Species Crossreactivity: mouse and rat