84-4093-99　GAR1 (NOLA1, H/ACA ribonucleoprotein complex subunit 1, Nucleolar protein family A member 1, snoRNP protein GAR1) 150ul　316848

特徴

• This gene is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family.
• snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA.
• The H/ACA snoRNPs also include the DKC1, NOLA2 and NOLA3 proteins.
• These four H/ACA snoRNP proteins localize to the dense fibrillar components of nucleoli and to coiled (Cajal) bodies in the nucleus.
• Both 18S rRNA production and rRNA pseudouridylation are impaired if any one of the four proteins is depleted.
• These four H/ACA snoRNP proteins are also components of the telomerase complex.
• The encoded protein of this gene contains two glycine- and arginine-rich domains and is related to Saccharomyces cerevisiae Gar1p.
• Two splice variants have been found for this gene.
• Applications:Suitable for use in ELISA, Western Blot and Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.