84-4052-08　Tumor necrosis factor ligand superfamily member 18 (TNFSF18) 50ul　338537

特徴

• Cytokine that binds to TNFRSF18/AITR/GITR.
• Regulates T-cell responses.
• Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation.
• Important for interactions between activated T-lymphocytes and endothelial cells.
• Mediates activation of NF-kappa-B.
• Triggers increased phosphorylation of STAT1 and up-regulates expression of VCAM1 and ICAM1 (PubMed:23892569).
• Promotes leukocyte adhesion to endothelial cells (PubMed:23892569).
• Regulates migration of monocytes from the splenic reservoir to sites of inflammation.
• Applications:Suitable for use in ELISA and Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Immunohistochemistry: 1:20-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.