84-4046-41 FADD (FAS-associated death domain Protein) 100ul 315716
特徴
- Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors.
- The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation.
- Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis.
- Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.
- Applications:Suitable for use in ELISA and Immunohistochemistry.
- Other applications not tested.
- Recommended Dilution:Immunohistochemistry: 1:20-1:200Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size：100ul
- Host：rabbit
- Source Antibody：human
- Grade：Affinity Purified
- Purity：Purified by immunoaffinity chromatography.
- Form：Supplied as a liquid in PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
- Specificity：Human
- Isotype：IgG
- Calc Applications Abbrev：E IHC
- Calc Crossreactivity：Hu
- Immunogen：Recombinant human FAS-associated death domain protein (aa1-208).
- Shelf Life：1year
- Swiss Prot Number：Q13158
- EU Commodity Code：30021010
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