84-4044-70　Huntingtin-interacting Protein 1 (HIP1) 50ul　319757

特徴

• Plays a role in clathrin-mediated endocytosis and trafficking.
• Involved in regulating AMPA receptor trafficking in the central nervous system in an NMDA-dependent manner.
• Enhances androgen receptor (AR)-mediated transcription.
• May act as a proapoptotic protein that induces cell death by acting through the intrinsic apoptosis pathway.
• Binds 3-phosphoinositides (via ENTH domain).
• May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis.
• May play a functional role in the cell filament networks.
• May be required for differentiation, proliferation, and/or survival of somatic and germline progenitors.
• Applications:Suitable for use in ELISA, Western Blot and Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:200-1000Immunohistochemistry: 1:20-1:200Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.