84-3993-63　Lysine-specific demethylase 5A (FITC) 50ug　322743

特徴

• Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code.
• Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'.
• Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'.
• May stimulate transcription mediated by nuclear receptors.
• May be involved in transcriptional regulation of Hox proteins during cell differentiation.
• May participate in transcriptional repression of cytokines such as CXCL12.
• Applications:Suitable for use in ELISA and Western Blot.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and StabilityStore product at 4°C if to be used immediately within two weeks.
• For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
• Aliquots are stable at -20°C for 12 months after receipt.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• Caution: FITC conjugates are sensitive to light.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.