84-3989-89　Protein disulfide-isomerase (FITC) 50ug　330859

特徴

• This multifunctional protein catalyzes the formation, breakage and rearrangement of disulfide bonds.
• At the cell surface, seems to act as a reductase that cleaves disulfide bonds of proteins attached to the cell.
• May therefore cause structural modifications of exofacial proteins.
• Inside the cell, seems to form/rearrange disulfide bonds of nascent proteins.
• At high concentrations, functions as a chaperone that inhibits aggregation of misfolded proteins.
• At low concentrations, facilitates aggregation (anti-chaperone activity).
• May be involved with other chaperones in the structural modification of the TG precursor in hormone biogenesis.
• Also acts a structural subunit of various enzymes such as prolyl 4-hydroxylase and microsomal triacylglycerol transfer protein MTTP
• Applications:Suitable for use in ELISA and Western Blot.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and StabilityStore product at 4°C if to be used immediately within two weeks.
• For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
• Aliquots are stable at -20°C for 12 months after receipt.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• Caution: FITC conjugates are sensitive to light.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.