84-3988-08 Echis carinatus Disintegrin EC3B 50ug 314319
特徴
- Inhibits adhesion of cells expressing alpha-4/beta-1 (ITGA4/ITGB1) and alpha-4/beta-7 (ITGA4/ITGB7) integrins to the natural ligands vascular cell adhesion molecule 1 (VCAM-1) and mucosal addressin cell adhesion molecule 1 (MADCAM-1).
- It is also a weaker inhibitor of alpha-5/beta-1 (ITGA5/ITGB1) and alpha-2b/beta-3 (ITGA2B/ITGB3) integrins.
- The inhibitory activity of EC3 towards alpha-4 integrins is associated with the MLD sequence of EC3B subunit.
- The ability of EC3 to inhibit ITGA5/ITGB1 resides in both subunits A and B.
- Applications:Suitable for use in ELISA and Western Blot.
- Other applications not tested.
- Recommended Dilution:Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size：50ug
- Host：rabbit
- Grade：Affinity Purified
- Purity：Purified by Protein G affinity chromatography.
- Form：Supplied as a liquid in 0.01M PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
- Specificity：Echis carinatus
- Isotype：IgG
- Calc Applications Abbrev：E WB
- Immunogen：Recombinant Echis carinatus Disintegrin EC3B protein
- Shelf Life：1year
- Swiss Prot Number：P81631
- EU Commodity Code：30021010
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