Appears to be involved in vesicular protein trafficking, mainly in the early secretory pathway.
In COPI vesicle-mediated retrograde transport involved in the coatomer recruitment to membranes of the early secretory pathway.
Increases coatomer-dependent activity of ARFGAP2.
Thought to play a crucial role in the specific retention of p24 complexes in cis-Golgi membranes, specifically contributes to the coupled localization of TMED2 and TMED10 in the cis-Golgi network.
May be involved in organization of intracellular membranes, such as of the ER-Golgi intermediate compartment and the Golgi apparatus.
Involved in ER localization of PTPN2 isoform PTPB.
Applications:Suitable for use in ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
Aliquots are stable at -20°C for 12 months after receipt.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ug
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by Protein G affinity chromatography.
Form:Supplied as a liquid in 0.01M PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol. Labeled with horseradish peroxidase (HRP)
Specificity:Human
Isotype:IgG
Calc Applications Abbrev:E WB
Calc Crossreactivity:Hu
Immunogen:Recombinant human Transmembrane emp24 domain-containing protein 9 protein