Appears to be involved in vesicular protein trafficking, mainly in the early secretory pathway.
In COPI vesicle-mediated retrograde transport involved in the coatomer recruitment to membranes of the early secretory pathway.
Increases coatomer-dependent activity of ARFGAP2.
Thought to play a crucial role in the specific retention of p24 complexes in cis-Golgi membranes, specifically contributes to the coupled localization of TMED2 and TMED10 in the cis-Golgi network.
May be involved in organization of intracellular membranes, such as of the ER-Golgi intermediate compartment and the Golgi apparatus.
Involved in ER localization of PTPN2 isoform PTPB.
Applications:Suitable for use in ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and StabilityStore product at 4°C if to be used immediately within two weeks.
For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
Aliquots are stable at -20°C for 12 months after receipt.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
Caution: FITC conjugates are sensitive to light.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:50ug
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by Protein G affinity chromatography.
Form:Supplied as a liquid in 0.01M PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol. Labeled with Fluorescein isothiocyanate (FITC).
Specificity:Human
Isotype:IgG
Calc Applications Abbrev:E WB
Calc Crossreactivity:Hu
Immunogen:Recombinant human Transmembrane emp24 domain-containing protein 9 protein