84-3952-41　Perforin-1 (Biotin) 100ug　327947

特徴

• Plays a key role in secretory granule-dependent cell death, and in defense against virus-infected or neoplastic cells.
• Plays an important role in killing other cells that are recognized as non-self by the immune system, e.g.
• in transplant rejection or some forms of autoimmune disease.
• Can insert into the membrane of target cells in its calcium-bound form, oligomerize and form large pores.
• Promotes cytolysis and apoptosis of target cells by facilitating the uptake of cytotoxic granzymes.
• Applications:Suitable for use in ELISA.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
• For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
• Aliquots are stable at -20°C for 12 months after receipt.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.