Active metalloproteinase with gelatinolytic and collagenolytic activity.
Plays a role in the wound healing process.
Mediates both heterotypic intraepithelial cell/T-cell interactions and homotypic T-cell aggregation.
Inhibits beta-1 integrin-mediated cell adhesion and migration of airway smooth muscle cells.
Suppresses cell motility on or towards fibronectin possibly by driving alpha-v/beta-1 integrin (ITAGV-ITGB1) cell surface expression via ERK1/2 inactivation.
Cleaves E-cadherin in response to growth factor deprivation.
Plays a role in glomerular cell migration.
Plays a role in pathological neovascularization.
May play a role in cartilage remodeling.
May be proteolytically processed, during sperm epididymal maturation and the acrosome reaction.
May play a role in sperm-egg binding through its disintegrin domain.
Applications:Suitable for use in ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and StabilityStore product at 4°C if to be used immediately within two weeks.
For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
Aliquots are stable at -20°C for 12 months after receipt.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
Caution: FITC conjugates are sensitive to light.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein G affinity chromatography.
Form：Supplied as a liquid in 0.01M PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol. Labeled with Fluorescein isothiocyanate (FITC).
Specificity：Human
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu
Immunogen：Recombinant human Disintegrin and metalloproteinase domain-containing protein 15 protein
