84-3920-76 ESRRA (Estrogen-Related Receptor alpha, ERR1, ERRa, ESRL1, NR3B1, ERRalpha) 50ul 335833
特徴
- Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'.
- Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter.
- Binds to the C1 region of the lactoferrin gene promoter.
- Requires dimerization and the coactivator, PGC-1A, for full activity.
- The ERRalpha/PGC1alpha complex is a regulator of energy metabolism.
- Induces the expression of PERM1 in the skeletal muscle.
- Applications:Suitable for use in ELISA and Immunohistochemistry.
- Other applications not tested.
- Recommended Dilution:Immunohistochemistry: 1:20-1:200Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size:50ul
- Host:rabbit
- Source Antibody:human
- Grade:Affinity Purified
- Purity:Purified by immunoaffinity chromatography.
- Form:Supplied as a liquid in PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
- Specificity:Human
- Isotype:IgG
- Calc Applications Abbrev:E IHC
- Calc Crossreactivity:Hu
- Immunogen:Recombinant human ESRRA (aa1-423)
- Shelf Life:1year
- Swiss Prot Number:P11474
- EU Commodity Code:30021010
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