84-3920-55 BANP (Btg3-associated Nuclear Protein, Scaffold/Matrix-associated Region-1-binding Protein, BEND1, SMAR1, SMARBP1) 100ul 330836
特徴
- Controls V(D)J recombination during T-cell development by repressing T-cell receptor (TCR) beta enhancer function.
- Binds to scaffold/matrix attachment region beta (S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR beta enhancer.
- Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels.
- Promotes TP53 'Ser-15' phosphorylation and nuclear accumulation, which causes cell cycle arrest.
- Applications:Suitable for use in ELISA, Western Blot and Immunohistochemistry.
- Other applications not tested.
- Recommended Dilution:Western Blot: 1:500-2000Immunohistochemistry: 1:20-1:200Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size：100ul
- Host：rabbit
- Source Antibody：human
- Grade：Affinity Purified
- Purity：Purified by immunoaffinity chromatography.
- Form：Supplied as a liquid in PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
- Specificity：Recognizes human BANP.
- Isotype：IgG
- Calc Applications Abbrev：E IHC WB
- Calc Crossreactivity：Hu
- Immunogen：Recombinant human Protein BANP protein (aa1-260)
- Shelf Life：1year
- Swiss Prot Number：Q8N9N5
- EU Commodity Code：30021010
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