Transcriptional repressor which binds to the consensus sequence 5'-GGTGTG-3'.
Plays a role in the regulation of the circadian clock, binds to the GC box sequence in the promoter of the core clock component ARTNL/BMAL1 and represses its transcriptional activity.
Regulates the circadian expression of genes involved in lipogenesis, gluconeogenesis, and glycolysis in the liver.
Represses the expression of PCK2, a rate-limiting step enzyme of gluconeogenesis (By similarity).
May play a role in the cell cycle regulation.
Applications:Suitable for use in ELISA.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Specificity：Human
Isotype：IgG
Calc Applications Abbrev：E
Calc Crossreactivity：Hu
Immunogen：Recombinant human Krueppel-like factor 10 protein (1-250aa)
