84-3891-41　TFAM (Transcription Factor A, Mitochondrial, mtTFA, Mitochondrial Transcription Factor 1, MtTF1, Transcription Factor 6, TCF-6, Transcription Factor 6-like 2, TFAM, TCF6, TCF6L20) (HRP) 50ug　336927

特徴

• Binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation.
• Required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase.
• Promotes transcription initiation from the HSP1 and the light strand promoter by binding immediately upstream of transcriptional start sites.
• Is able to unwind DNA.
• Bends the mitochondrial light strand promoter DNA into a U-turn shape via its HMG boxes.
• Required for maintenance of normal levels of mitochondrial DNA.
• May play a role in organizing and compacting mitochondrial DNA.
• Applications:Suitable for use in ELISA, Western Blot and Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
• For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
• Aliquots are stable at -20°C for 12 months after receipt.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.