CD101 is a disulfide-linked homodimeric polypeptide.
The gene encoding the CD101 antigen is identical to the gene encoding for the V7 antigen, which corresponds to a type I transmembrane protein containing seven Ig-like loops in its extracellular domain.
CD101 may play an important regulatory role during T cell activation and may also be useful in combination with other markers for the diagnosis of LCH (Langerhans cell histiocytosis).
CD101 is expressed on monocytes, granulocytes, dendritic cells and at low levels on a subset of peripheral T-cells comprising both CD4+ and CD8+, as well as both CD45RA+ and CD45RO+ cells.
Expression of CD101 increases upon T cell activation.
Applications:Suitable for use in ELISA and Western Blot.
Other applications not tested.
Recommended Dilution:ELISA: 1:10,000Western Blot: 1:500-1:2000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.5% BSA, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes human CD101.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to the Internal region of human CD101.
