84-3771-76 ADRB2 (Beta-2 Adrenergic Receptor, Beta-2 Adrenoreceptor, Beta-2 Adrenoceptor, ADRB2R, B2AR) 100ug 306587
特徴
- This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily.
- This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2.
- This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A.
- The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor.
- This gene is intronless.
- Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes.
- Applications:Suitable for use in ELISA and Western Blot.
- Other applications not tested.
- Recommended Dilution:ELISA: 1:5000Western Blot: 1:500-1:2000Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size:100ug
- Host:rabbit
- Source Antibody:human
- Grade:Affinity Purified
- Purity:Purified by immunoaffinity chromatography.
- Form:Supplied as a liquid in PBS, 0.5% BSA, 0.02% sodium azide, 50% glycerol.
- Specificity:Recognizes human ADRB2. Species Crossreactivity: mouse and rat
- Isotype:IgG
- Calc Applications Abbrev:E WB
- Calc Crossreactivity:Hu Mo Rt
- Immunogen:Synthetic peptide corresponding to human AR-beta2 around the non-phosphorylation site of S355/S356.
- Shelf Life:1year
- Swiss Prot Number:P07550
- EU Commodity Code:30021010
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