84-3755-16　ID4, NT (DNA-Binding Protein Inhibitor ID-4, Class B basic Helix-Loop-Helix Protein 27, bHLHb27, Inhibitor of DNA Binding 4, ID4, BHLHB27) 100ug　319887

特徴

• DNA-binding protein inhibitor ID-4 is a protein that in humans is encoded by the ID4 gene.
• Transcription factors containing a basic helix-loop-helix (bHLH) motif regulate expression of tissue-specific genes in a number of mammalian and insect systems.
• DNA-binding activity of the bHLH proteins is dependent on formation of homo- and/or heterodimers.
• Dominant-negative (antimorph) HLH proteins encoded by Id-related genes, such as ID4, also contain the HLH-dimerization domain but lack the DNA-binding basic domain.
• Consequently, Id proteins inhibit binding to DNA and transcriptional transactivation by heterodimerization with bHLH proteins.
• Applications:Suitable for use in ELISA, Western Blot and Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:ELISA: 1:20,000Western Blot: 1:500-1:2000Immunohistochemistry: 1:100-1:300Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.