Heat shock protein 105kD is a protein that in humans is encoded by the HSPH1 gene.
Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly.
Inhibits HSPA8/HSC70 ATPase and chaperone activities.
Highly expressed in testis.
Present at lower levels in most brain regions, except cerebellum.
Overexpressed in cancer cells.
Phosphorylation on Ser-509 may be important for regulation of the HSPA8/HSC70 chaperone activity.
Applications:Suitable for use in Immunofluorescence, ELISA, Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunofluorescence: 1:200-1:1000ELISA: 1:10,000Western Blot: 1:500-1:2000Immunohistochemistry: 1:100-1:300Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.5% BSA, 0.02% sodium azide, 50% glycerol.
Specificity：Recognizes human HSP105. Species Crossreactivity: mouse
Isotype：IgG
Calc Applications Abbrev：E IF IHC WB
Calc Crossreactivity：Hu Mo
Immunogen：Synthetic peptide corresponding to the C-terminal of human HSP105.
