84-3737-49　Tubulin, alpha, acetylated (K112) (Alpha Tubulin, Tubulin alpha Ubiquitous, H2-Alpha, K-alpha-1, TUBA3, Tubulin alpha 1 Chain, TUBA1, TUBA1A, Tubulin K alpha 1) 50ug　304372

特徴

• Tubulin is a major cytoskeleton component that has three distinct forms, designated alpha, beta and y Tubulin.
• alpha and beta Tubulins form heterodimers, which multimerize to form a microtubule filament.
• y Tubulin forms a soluble multiprotein particle with several other proteins.
• This particle, designated the gammasome, is required for nucleating microtubule filaments at the centrosome.
• In several organisms, numerous isoforms of the Tubulins exist that are encoded by different genes.
• The alpha and beta isoforms undergo a variety of post-translational modifications, which may affect microtubule stability and protein interactions.
• High expression of class II beta Tubulin has been seen in elongating axons, indicating a role in neurite outgrowth.
• Tubulins may also play a role in non-neuronal cell process formation.
• Applications:Suitable for use in Western Blot and ELISA.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500-1:2000ELISA: 1:20,000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.