The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta.
The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication.
In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway.
Two transcript variants encoding the same protein have been found for this gene.
Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome.
Applications:Suitable for use in ELISA, Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:ELISA: 1:500-1:5000Immunohistochemistry: 1:25-1:100 Western Blot: 1:500-1:2000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Specificity：Recognizes human PCNA. Species Crossreactivity: mouse and rat
Isotype：IgG
Calc Applications Abbrev：E IHC WB
Calc Crossreactivity：Hu Mo Rt
Immunogen：Fusion protein corresponding to a region derived from aa9-252 of human Proliferating cell nuclear antigen.
