84-3694-41 XRCC5 (Ku80, X Ray Repair Complementing Defective Repair in Chinese Hamster Cells 5 (Double-strand-break Rejoining), Heterodimer of Ku80 Subunits, Ku-80, Ku 80) (HRP) 100ul 301498-HRP
84-3694-41 XRCC5 (Ku80, X Ray Repair Complementing Defective Repair in Chinese Hamster Cells 5 (Double-strand-break Rejoining), Heterodimer of Ku80 Subunits, Ku-80, Ku 80) (HRP) 100ul 301498-HRP
The DNA repair protein Ku (a heterodimer of Ku70 and Ku80 subunits) associates with mammalian telomeres and contributes to telomere maintenance.
The Ku heterodimer functions at two kinds of DNA ends: telomeres and double-strand breaks.
The role that Ku plays at these two classes of termini must be distinct, because Ku is required for accurate and efficient joining of double-strand breaks while similar DNA repair events are normally prohibited at chromosome ends.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
Aliquots are stable at -20°C for 12 months after receipt.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size:100ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with horseradish peroxidase (HRP).
Specificity:Recognizes XRCC5. Species Crossreactivity: hamster, human, mouse and rat
Isotype:IgG
Calc Applications Abbrev:WB
Calc Crossreactivity:Hm Hu Mo Rt
Immunogen:Residues aa323-338 [FSKVDEEQMKYKSEGK] of 80kD XRCC5.