Beta 2 Microglobulin is a low molecular weight protein with sequence homology to immunoglobulins.
As a portion of the HLA complex this protein is an important cell-surface structure.
Under normal conditions Beta 2 Microglobulin is synthesized and shed by many cells, particularly lymphocytes, and is detectable in the circulation of normal individuals.
Because of its small size it is normally filtered readily at the glomerulus and is catabolized by proximal tubular cells of the kidney.
Impaired renal function and hyperproduction of Beta 2 Microglobulin are both associated with increased serum levels.
A function for Beta 2 Microglobulin as a modulator of lymphocyte surface and as a potential regulator of the immune system is proposed.
Applications:Suitable for use in ELISA.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
Aliquots are stable at -20°C for 12 months after receipt.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size：100ul
Host：goat
Source Antibody：human
Grade：Affinity Purified
Purity：Affinity Purified
Form：Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
Specificity：Recognizes human beta 2 Microglobulin.
