84-3676-55　［取扱停止］Transforming Growth Factor beta (Latency-associated Peptide, TGFb, LAP) (Biotin) 100ul　T8250-12-Biotin

特徴

• Transforming growth factor-beta (TGFb) family of proteins has potent hematopoietic regulatory properties ranging from effects on the growth and differentiation of primitive stem cells to the differentiated functions of mature cells.
• Although most reports have described the inhibitory activities of TGF-beta on hematopoiesis, recent evidence supports the concept that TGF-beta can have both inhibitory and stimulatory actions on these systems.
• These differences depend on the differentiation state of the target cell and the other cytokines interacting with the cell.
• Furthermore, TGF-beta has direct bidirectional effects on cell surface expression of many cytokine receptors suggesting that it is part of the mechanism of action of TGF-beta.
• Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry and Neutralization.
• Other applications have not been tested.
• Recommended Dilutions:Immunohistochemistry: using immersion fixed paraffin-embedded sections of human prostate cancer tissueImmunocytochemistry: using immersion fixed human peripheral blood mononuclear cells (PBMCs) Optimal dilutions to be determined by the researcher.
• Storage and Stability:Store product at 4°C if to be used immediately within two weeks.
• For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C.
• Aliquots are stable at -20°C for 12 months after receipt.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Note: Applications are based on unconjugated antibody.