84-3675-44　PARK2 (Juvenile Parkinson Disease Autosomal Recessive 2, Parkinson Disease Autosomal Recessive 2, PARK 2, PARK-2, Parkin) (APC) 100ul　301444-APC

特徴

• Mutations in the gene, Parkin (PARK2), appear to be responsible for the pathogenesis of autosomal recessive juvenile Parkinsonism.
• Parkin plays a role in the ubiquitin-mediated proteolytic pathway by removal and/or detoxification of abnormally folded or damaged protein.
• Loss of this ubiquitin ligase activity appears to be the mechanism underlying pathogenesis of Parkin.
• Applications:Suitable for use in Immunoprecipitation and Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:250-1:1000Immunoprecipitation: 1:250-1:1000Optimal dilutions to be determined by the researcher.
• Storage and Stability:Store product at 4°C in the dark.
• DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• Caution: APC conjugates are sensitive to light.
• For maximum recovery of product, centrifuge the original vial prior to removing the cap.
• Note: Applications are based on unconjugated antibody.