Interferon-gamma (IFN-gamma) is an inflammatory cytokine that has been implicated in the development of fibrosis in inflamed tissues.
The production of IFN-gamma, which is under genetic control, can influence the development of fibrosis in lung allografts.
IFN-gamma is also produced by natural killer (NK) cells and most prominently by CD8 cytotoxic T cells, and is vital for the control of microbial pathogens.
Interferon gamma is believed to be crucial for host defence against many infections.
Genetically determined variability in IFN-gamma and expression might be important for the development of tuberculosis.
IFN-gamma activates human macrophage oxidative metabolism and antimicrobial activity.
In addition to having antiviral activity, IFN-gamma has important immunoregulatory functions.
IFN-gamma plays an important role in the control of neointima proliferation.
UniProt Number:P01581
Gene ID:IFNG
Applications:Suitable for use in FLISA, Western Blot, Immunohistochemistry (Paraffin), Neutralization and Immunoprecipitation.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:Store product at 4°C in the dark.
DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
Caution: MaxLight™550 conjugates are sensitive to light.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size：100ul
Host：rabbit
Source Antibody：rat
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight™550.
Specificity：Recognizes rat IFN gamma. No crossreactivity with other proteins.
Isotype：IgG
Calc Applications Abbrev：FLISA IHC IP N WB
Calc Crossreactivity：Rt
Immunogen：E. coli-derived rat IFNgamma recombinant protein (Position: 23-156).
