CEA(Carcinoembryonic antigen) is a glycoprotein involved in cell adhesion.
It is normally produced during fetal development, but the production of CEA stops before birth.
Therefore, it is not usually present in the blood of healthy adults, although levels are raised in heavy smokers.
CEA is a glycosyl phosphatidyl inositol (GPI)-cell surface anchored glycoprotein whose specialized sialofucosylated glycoforms serve as functional colon carcinoma L-selectin and E-selectin ligands, which may be critical to the metastatic dissemination of colon carcinoma cells.
CEA and related genes make up the CEA family belonging to the immunoglobulin superfamily.
In humans, the carcinoembryonic antigen family consists of 29 genes, 18 of which are normally expressed.
UniProt Number:P06731
Gene ID:CEACAM5
Applications:Suitable for use in FLISA, Western Blot and Immunohistochemistry (Paraffin).
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:Store product at 4°C in the dark.
DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
Caution: MaxLight™550 conjugates are sensitive to light.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight™550.
Specificity：Recognizes human CEA . No crossreactivity with other proteins.
Isotype：IgG
Calc Applications Abbrev：FLISA IHC WB
Calc Crossreactivity：Hu
Immunogen：Insect cells-derived human CEA recombinant protein (Position: full).
