Immunoreactive BCL2 protein in the neoplastic cells of almost all follicular lymphomas whereas no BCL2 protein was detected in follicles affected by nonneoplastic processes or in normal lymphoid tissue.
Every tumor with molecular-genetic evidence of t(14;18) translocation expressed detectable levels of BCL2 protein, regardless of whether the breakpoint was located in or at a distance from the BCL2 gene.
Overexpression of BCL2 blocks the apoptotic death of a pro-B-lymphocyte cell line.
UniProt Number:P10415
Gene ID:BCL2
Applications:Suitable for use in FLISA, Western Blot, Neutralization and Immunoprecipitation.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:Store product at 4°C in the dark.
DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
Caution: MaxLight™550 conjugates are sensitive to light.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight™550.
Specificity：Recognizes human BCL-2. No crossreactivity with other proteins.
Isotype：IgG
Calc Applications Abbrev：FLISA IP N WB
Calc Crossreactivity：Hu
Immunogen：E. coli-derived human BCL-2 recombinant protein (Position: M1-D211).
