MaxLight™ 490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection.
Interferon-gamma (IFN-gamma) is an inflammatory cytokine that has been implicated in the development of fibrosis in inflamed tissues.
The production of IFN-gamma, which is under genetic control, can influence the development of fibrosis in lung allografts.
IFN-gamma is also produced by natural killer (NK) cells and most prominently by CD8 cytotoxic T cells, and is vital for the control of microbial pathogens.
Interferon gamma is believed to be crucial for host defence against many infections.
Genetically determined variability in IFN-gamma and expression might be important for the development of tuberculosis.
IFN-gamma activates human macrophage oxidative metabolism and antimicrobial activity.
In addition to having antiviral activity, IFN-gamma has important immunoregulatory functions.
IFN-gamma plays an important role in the control of neointima proliferation.
Applications:Suitable for use in FLISA and Western Blot.
Other applications not tested.
Recommended Dilution:FLISA: 0.1-0.5ug/mlWestern Blot: 0.1-0.5ug/ml, the detection limit is ~0.25ng/lane under reducing conditions
Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at -20°C.
Stable for 12 months after receipt at -20°C.
Reconstitute with sterile ddH2O.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Reconstituted product is stable for 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
Note: Applications are based on unconjugated antibody.
仕様
Size：100ul
Host：rabbit
Source Antibody：rat
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight™490.
Specificity：Recognizes rat Interferon gamma.
Isotype：IgG
Calc Applications Abbrev：FLISA WB
Calc Crossreactivity：Rt
Immunogen：Recombinant protein corresponding to rat Interferon gamma expressed in E. coli. (Position: Q23-C156). Species sequence homology: human (38%) and mouse (86%)
