84-3647-33　［取扱停止］Survivin (API4, IAP4, Apoptosis inhibitor 4, Apoptosis inhibitor survivin, EPR-1, survivin, survivin variant 3 alpha, baculoviral IAP repeat-containing 5, ) (MaxLight 490) 100ul　145241-ML490

特徴

• MaxLight™ 490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection.
• Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000.
• Survivin, also called baculoviral inhibitor of apoptosis repeat-containing 5 or BIRC5, is a protein that, in humans, is encoded by the BIRC5 gene.
• Survivin is a member of the inhibitor of apoptosis (IAP) family.
• The survivin gene contains 4 exons.
• The survivin gene is mapped to chromosome 17q25 by pulsed field gel electrophoresis and single- and 2-color FISH.
• The survivin protein functions to inhibit caspase activation, thereby leading to negative regulation of apoptosis or programmed cell death.
• The survivin protein is expressed highly in most human tumors and fetal tissue, but is completely absent in terminally differentiated cells.
• UniProt Number:O15392
• Gene ID:BIRC5
• Applications:Suitable for use in FLISA, Western Blot and Immunohistochemistry (Paraffin).
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:Store product at 4°C in the dark.
• DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• Caution: MaxLight™490 conjugates are sensitive to light.
• For maximum recovery of product, centrifuge the original vial prior to removing the cap.
• Note: Applications are based on unconjugated antibody.