84-3647-24　IL-6 (B Cell stimulatory factor 2) (MaxLight 490) 100ul　144747-ML490

特徴

• MaxLight™ 490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection.
• Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000.
• Interleukin-6 (IL-6) is a protein that in humans is encoded by the IL6 gene.
• IL-6 is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine.
• It is secreted by T cells and macrophages to stimulate immune response to trauma, especially burns or other tissue damage leading to inflammation.
• IL-6 is one of the most important mediators of fever and of the acute phase response.
• IL-6 is also essential for hybridoma growth and is found in many supplemental cloning media such as briclone.
• Bowcock et al.
• (1988) assigned the IL6 gene to chromosome 7p21.
• By in situ hybridization and Southern blot analysis of mouse-human hybrid cell lines, Sutherland et al.
• (1988) mapped the IL-6 gene to chromosome 7p15.
• UniProt Number:P05231
• Gene ID:IL6
• Applications:Suitable for use in Western Blot.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:Store product at 4°C in the dark.
• DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• Caution: MaxLight™490 conjugates are sensitive to light.
• For maximum recovery of product, centrifuge the original vial prior to removing the cap.
• Note: Applications are based on unconjugated antibody.