Interferon-gamma (IFN-gamma) is an inflammatory cytokine that has been implicated in the development of fibrosis in inflamed tissues.
The production of IFN-gamma, which is under genetic control, can influence the development of fibrosis in lung allografts.
IFN-gamma is also produced by natural killer (NK) cells and most prominently by CD8 cytotoxic T cells, and is vital for the control of microbial pathogens.
Interferon gamma is believed to be crucial for host defence against many infections.
Genetically determined variability in IFN-gamma and expression might be important for the development of tuberculosis.
IFN-gamma activates human macrophage oxidative metabolism and antimicrobial activity.
In addition to having antiviral activity, IFN-gamma has important immunoregulatory functions.
IFN-gamma plays an important role in the control of neointima proliferation.
UniProt Number:P01581
Gene ID:IFNG
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry (Paraffin), Neutralization and Immunoprecipitation.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Handling:Store at -20˚C for one year.
After reconstitution, store at 4˚C for one month.
Can also be aliquoted and stored frozen at -20˚C for long term
Avoid repeated freezing and thawing.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size:100ul
Host:rabbit
Source Antibody:rat
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.2. Labeled with horseradish peroxidase (HRP).
Specificity:Recognizes rat IFN gamma. No crossreactivity with other proteins.
Isotype:IgG
Calc Applications Abbrev:E IHC IP N WB
Calc Crossreactivity:Rt
Immunogen:E. coli-derived rat IFNgamma recombinant protein (Position: 23-156).