CEA(Carcinoembryonic antigen) is a glycoprotein involved in cell adhesion.
It is normally produced during fetal development, but the production of CEA stops before birth.
Therefore, it is not usually present in the blood of healthy adults, although levels are raised in heavy smokers.
CEA is a glycosyl phosphatidyl inositol (GPI)-cell surface anchored glycoprotein whose specialized sialofucosylated glycoforms serve as functional colon carcinoma L-selectin and E-selectin ligands, which may be critical to the metastatic dissemination of colon carcinoma cells.
CEA and related genes make up the CEA family belonging to the immunoglobulin superfamily.
In humans, the carcinoembryonic antigen family consists of 29 genes, 18 of which are normally expressed.
UniProt Number:P06731
Gene ID:CEACAM5
Applications:Suitable for use in ELISA, Western Blot and Immunohistochemistry (Paraffin).
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Handling:Store at -20˚C for one year.
After reconstitution, store at 4˚C for one month.
Can also be aliquoted and stored frozen at -20˚C for long term
Avoid repeated freezing and thawing.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2. Labeled with horseradish peroxidase (HRP).
Specificity：Recognizes human CEA . No crossreactivity with other proteins.
Isotype：IgG
Calc Applications Abbrev：E IHC WB
Calc Crossreactivity：Hu
Immunogen：Insect cells-derived human CEA recombinant protein (Position: full).
