ADIPOQ (Adipocyte-, C1q-, and Collagen Domain-Containing), also known as APM1, ADPN or ACDC, is a protein which in humans is encoded by the ADIPOQ gene.
Using FISH, Das et al.
(2001) mapped the mouse Acrp30 gene to chromosome 16 in a region showing homology of synteny with human 3q27.
By RNase protection and Western blot analysis, Schaffler et al.
(1999) showed that APM1 is expressed by differentiated adipocytes as a 33-kD protein that is also detectable in serum.
By sequence comparisons, they found links between APM1 and TNF family ligands as well as to cytokines expressed by T cells.
Adiponectin is a protein hormone that modulates a number of metabolic processes, including glucose regulation and fatty acid oxidation.
Adiponectin is exclusively secreted from adipose tissue (and also from the placenta in pregnancy) into the bloodstream and is very abundant in plasma relative to many hormones.
UniProt Number:Q15848
Gene ID:ADIPOQ
Applications:Suitable for use in Western Blot.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Handling:Store at -20˚C for one year.
After reconstitution, store at 4˚C for one month.
Can also be aliquoted and stored frozen at -20˚C for long term
Avoid repeated freezing and thawing.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size:100ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.2. Labeled with horseradish peroxidase (HRP).
Specificity:Recognizes human ADIPOQ. No crossreactivity with other proteins.
Isotype:IgG
Calc Applications Abbrev:WB
Calc Crossreactivity:Hu
Immunogen:E. coli-derived human ADIPOQ recombinant protein (Position: E19-N244).