84-3605-79 [取扱停止]XRN1 (5'-3' exoribonuclease 1, 3113-, Strand-Exchange Protein 1 Homolog, XRN1, SEP1) (MaxLight 550) 100ul 302847-ML550
特徴
MaxLight™ 550 is a new Yellow-Green photostable dye conjugate comparable to Alexa Fluor™546, 555, DyLight™549 , Cy3™, TRITC and offers better labeling efficiency, brighter imaging and increased immunodetection.
Absorbance (550nm); Emission (575nm); Extinction Coefficient 150,000.
Major 5'-3' exoribonuclease involved in mRNA decay.
Required for the 5'-3'-processing of the G4 tetraplex-containing DNA and RNA substrates.
The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex.
Binds to RNA and DNA (By similarity).
Plays a role in replication-dependent histone mRNA degradation.
May act as a tumor suppressor protein in osteogenic sarcoma (OGS).
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:2000Optimal dilutions to be determined by the researcher.
Storage and Stability:Store product at 4°C in the dark.
DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
Caution: MaxLight™550 conjugates are sensitive to light.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
仕様
Size:100ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by Protein A affinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™550.
Specificity:Recognizes human XRN1. Species Crossreactivity: human
Isotype:IgG
Calc Applications Abbrev:WB
Calc Crossreactivity:Hu
Immunogen:KLH conjugated synthetic peptide corresponding to aa1389-1423 at the C-terminal region of human XRN1.
Shelf Life:1year
Swiss Prot Number:Q8IZH2
EU Commodity Code:30021010
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