MaxLight™ 490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection.
The CBL oncogene was first identified as part of a transforming retrovirus which induces mouse pre-B and pro-B cell lymphomas.
As an adaptor protein for receptor protein-tyrosine kinases, it positively regulates receptor protein-tyrosine kinase ubiquitination in a manner dependent upon its variant SH2 and RING finger domains.
Ubiquitination of receptor protein-tyrosine kinases terminates signaling by marking active receptors for degradation.
Applications:Suitable for use in Western Blot, Flow Cytometry (Not Tested), FLISA