84-3573-41　［取扱停止］DSG2, NT (T160) (Desmoglein-2, HDGC, Cadherin Family Member 5, CDHF5) (MaxLight 490) 100ul　D3221-83G-ML490

特徴

• MaxLight™ 490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection.
• Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000.
• Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types.
• This protein is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells.
• Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily.
• These desmoglein gene family members are located in a cluster on chromosome 18.
• This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines.
• Mutations in the DSG2 gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10.
• Applications:Suitable for use in FLISA, Western Blot, and Flow Cytometry (Not Tested).
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:50-1:100FLISA: 1:1,000Flow Cytometry (Not Tested): 1:10-1:50Optimal dilutions to be determined by the researcher.
• Storage and Stability:Store product at 4°C in the dark.
• DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• Caution: MaxLight™490 conjugates are sensitive to light.
• For maximum recovery of product, centrifuge the original vial prior to removing the cap.
• Note: Applications are based on unconjugated antibody.